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Maddrey's Discriminant Function Calculator

Result

Calculated result 44.8 Based on the values entered.
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Maddrey's Discriminant Function Calculator — free online calculator.

Formula

DF = 4.6 × (patient PT − control PT) + serum bilirubin
  • Maddrey's Discriminant Function Calculator calculates its result from Patient prothrombin time, Control prothrombin time, Serum bilirubin. It uses the formula DF = 4.6 × (patient PT − control PT) + serum bilirubin. Change any input to recalculate the result instantly. This is an informational calculation and is not medical advice.
  • The main inputs are Patient prothrombin time, Control prothrombin time, Serum bilirubin. Enter them in the units and format shown in the calculator.
  • Use the measurement units shown beside each field. The result is an estimate and should be interpreted in context.
  • Changing any input above recalculates the result with the same calculation engine used by this page.

Example: Maddrey's Discriminant Function

Inputs
  • Patient prothrombin time: 20
  • Control prothrombin time: 12
  • Serum bilirubin: 8

Using Patient prothrombin time = 20, Control prothrombin time = 12, Serum bilirubin = 8, the calculated result is 44.8.

Sample result: Calculating…

Frequently asked questions

What does the Maddrey's Discriminant Function calculate?

Maddrey's Discriminant Function Calculator — free online calculator.

Which values should I enter?

Enter Patient prothrombin time, Control prothrombin time, Serum bilirubin using the units and format shown beside each field.

What formula does this calculator use?

The calculator uses the following relationship: DF = 4.6 × (patient PT − control PT) + serum bilirubin.

Why might my result differ from another source?

Results can differ because measurement methods, rounding and assumptions vary. This calculator is an estimate and is not a medical diagnosis.

Does the result update automatically?

Yes. Changing an input updates the result using the same calculation engine shown on this page.

Page information

Updated: October 7, 2026